@font-face {
  font-family: "Lyon Display";
  src:
    url("assets/fonts/LyonDisplay-RegularItalic.woff2") format("woff2"),
    url("assets/fonts/LyonDisplay-RegularItalic.woff") format("woff");
  font-style: italic;
  font-weight: 400;
  font-display: swap;
}

:root {
  --ochre: #e64626;
  --accessible-ochre: #ce3d20;
  --sandstone: #fcede2;
  --heritage-rose: #daa8a2;
  --jacaranda: #8f9ec9;
  --navy: #1a355e;
  --eucalypt: #71a499;
  --charcoal: #424242;
  --light-grey: #f1f1f1;

  --ink: #000000;
  --muted: var(--charcoal);
  --line: #d8d8d8;
  --surface: #ffffff;
  --page: var(--light-grey);
  --primary: var(--accessible-ochre);
  --primary-hover: var(--ochre);
  --primary-soft: var(--sandstone);
  --analysis-accent: var(--navy);
  --stability-accent: var(--jacaranda);
  --risk-high: var(--ochre);
  --risk-moderate: var(--signal-high-soft);
  --risk-low: var(--jacaranda);
  --signal-high: var(--accessible-ochre);
  --signal-high-soft: var(--heritage-rose);
  --signal-low: var(--navy);
  --signal-low-soft: var(--jacaranda);
  --signal-neutral: var(--light-grey);
  --metric-strong: var(--risk-high);
  --metric-adequate: var(--risk-moderate);
  --metric-limited: var(--risk-low);
  --shadow: 0 16px 40px rgba(0, 0, 0, 0.08);

  --sidebar-bg: rgba(252, 237, 226, 0.82);
  --sidebar-bg-top: rgba(252, 237, 226, 0.94);
  --sidebar-text: var(--charcoal);
  --sidebar-muted: rgba(66, 66, 66, 0.68);
  --sidebar-border: rgba(206, 61, 32, 0.16);
  --sidebar-hover: rgba(206, 61, 32, 0.08);
  --sidebar-active: rgba(206, 61, 32, 0.14);
  --sidebar-width: 268px;
  --sidebar-collapsed-width: 80px;
  --font-sans: "Apercu Pro", "Apercu", "Source Sans Pro", Arial, sans-serif;
  --font-display: "Lyon Display", "Times New Roman", serif;
  --font-mono: "Apercu Pro Mono", ui-monospace, SFMono-Regular, Menlo, monospace;
}

* {
  box-sizing: border-box;
}

body {
  margin: 0;
  color: var(--ink);
  background: var(--page);
  font-family: var(--font-sans);
  letter-spacing: 0;
}

button,
input,
select {
  font: inherit;
}

button {
  cursor: pointer;
}

.app-shell {
  display: grid;
  grid-template-columns: var(--sidebar-width) minmax(0, 1fr);
  min-height: 100vh;
  transition: grid-template-columns 200ms ease;
}

.app-shell.sidebar-collapsed {
  grid-template-columns: var(--sidebar-collapsed-width) minmax(0, 1fr);
}

.sidebar {
  display: flex;
  flex-direction: column;
  gap: 0;
  padding: 20px 14px;
  color: var(--sidebar-text);
  background: linear-gradient(180deg, var(--sidebar-bg-top) 0%, var(--sidebar-bg) 100%);
  backdrop-filter: blur(8px);
  border-right: 1px solid var(--sidebar-border);
  box-shadow: 4px 0 28px rgba(0, 0, 0, 0.06);
  transition: padding 200ms ease;
}

.sidebar-collapsed .sidebar {
  padding: 16px 10px;
}

.brand-block {
  display: grid;
  grid-template-columns: 36px 1fr 36px;
  gap: 12px;
  align-items: center;
  padding: 4px 6px 20px;
  margin-bottom: 8px;
  border-bottom: 1px solid var(--sidebar-border);
}

.brand-mark {
  display: grid;
  width: 36px;
  height: 36px;
  place-items: center;
  border-radius: 9px;
  background: linear-gradient(145deg, var(--ochre), var(--accessible-ochre));
  color: #ffffff;
  box-shadow: 0 6px 16px rgba(0, 0, 0, 0.22);
}

.brand-mark svg {
  display: block;
}

.brand-eyebrow {
  margin: 0 0 4px;
  color: var(--sidebar-muted);
  font-size: 0.68rem;
  font-weight: 600;
  letter-spacing: 0.1em;
  text-transform: uppercase;
}

.brand-title {
  margin: 0;
  color: var(--sidebar-text);
  font-size: 1.02rem;
  font-weight: 600;
  line-height: 1.25;
  letter-spacing: 0;
}

.sidebar-toggle {
  display: grid;
  width: 36px;
  height: 36px;
  place-items: center;
  border: 1px solid var(--sidebar-border);
  border-radius: 9px;
  background: rgba(255, 255, 255, 0.5);
  color: var(--sidebar-text);
  transition: background 150ms ease, border-color 150ms ease;
}

.sidebar-toggle:hover {
  background: var(--sidebar-hover);
  border-color: rgba(206, 61, 32, 0.34);
}

.sidebar-toggle-icon {
  display: block;
  transition: transform 200ms ease;
}

.sidebar-collapsed .sidebar-toggle-icon {
  transform: rotate(180deg);
}

.sidebar-collapsed .brand-block {
  grid-template-columns: 1fr;
  justify-items: center;
  gap: 10px;
  padding-bottom: 16px;
}

.sidebar-collapsed .brand-text,
.sidebar-collapsed .nav-label,
.sidebar-collapsed .nav-section-label {
  display: none;
}

.eyebrow,
.micro-label {
  margin: 0;
  color: var(--muted);
  font-size: 0.75rem;
  font-weight: 700;
  text-transform: uppercase;
}

.sidebar .eyebrow,
.sidebar .micro-label {
  color: var(--sidebar-muted);
}

h1,
h2,
h3,
p {
  margin-top: 0;
}

h1,
h2,
h3 {
  font-family: var(--font-sans);
  font-weight: 600;
  letter-spacing: 0;
}

h1 {
  margin-bottom: 0;
  font-size: 1.05rem;
}

h2 {
  margin-bottom: 0;
  font-size: 1.8rem;
}

h3 {
  margin-bottom: 0;
  font-size: 1.05rem;
}

.sidebar-nav {
  flex: 1;
  padding: 8px 6px 0;
}

.nav-section-label {
  margin: 0 0 10px;
  padding: 0 10px;
  color: var(--sidebar-muted);
  font-size: 0.68rem;
  font-weight: 600;
  letter-spacing: 0.08em;
  text-transform: uppercase;
}

.nav-list {
  display: grid;
  gap: 4px;
}

.nav-item {
  position: relative;
  display: grid;
  grid-template-columns: 36px 1fr;
  align-items: center;
  gap: 12px;
  width: 100%;
  min-height: 44px;
  padding: 8px 6px 8px 0;
  border: 0;
  border-radius: 10px;
  color: var(--sidebar-text);
  background: transparent;
  font-size: 0.9rem;
  font-weight: 500;
  text-align: left;
  transition: background 150ms ease, color 150ms ease, box-shadow 150ms ease, transform 150ms ease;
}

.sidebar-collapsed .nav-item {
  grid-template-columns: 1fr;
  justify-items: center;
  padding: 10px 8px;
}

.nav-item:hover,
.nav-item:focus-visible {
  color: var(--accessible-ochre);
  background: transparent;
  box-shadow: none;
  outline: 0;
}

.nav-item.active {
  color: var(--accessible-ochre);
  background: transparent;
  box-shadow: none;
}

.nav-item.active:hover,
.nav-item.active:focus-visible {
  background: transparent;
  box-shadow: none;
}

.nav-icon {
  display: grid;
  width: 36px;
  height: 36px;
  place-items: center;
  border: 1px solid transparent;
  border-radius: 9px;
  background: rgba(255, 255, 255, 0.52);
  color: var(--navy);
  transition: background 150ms ease, border-color 150ms ease, color 150ms ease, box-shadow 150ms ease, transform 150ms ease;
}

.nav-item:hover .nav-icon,
.nav-item:focus-visible .nav-icon {
  border-color: rgba(206, 61, 32, 0.42);
  background: rgba(206, 61, 32, 0.1);
  color: var(--accessible-ochre);
  box-shadow: none;
  transform: translateY(-1px);
}

.nav-item.active .nav-icon {
  border-color: rgba(206, 61, 32, 0.72);
  background: rgba(206, 61, 32, 0.14);
  color: var(--accessible-ochre);
}

.nav-item.active:hover .nav-icon,
.nav-item.active:focus-visible .nav-icon {
  box-shadow: none;
}

.nav-icon svg {
  display: block;
}

.sidebar-footer {
  margin-top: auto;
  padding: 18px 10px 6px;
  border-top: 1px solid var(--sidebar-border);
}

.sidebar-collapsed .sidebar-footer {
  display: grid;
  justify-items: center;
  padding: 14px 0 4px;
}

.backend-status {
  display: flex;
  align-items: flex-start;
  gap: 10px;
  margin: 0 0 12px;
  padding: 10px 12px;
  border: 1px solid var(--sidebar-border);
  border-radius: 10px;
  background: rgba(255, 255, 255, 0.5);
  color: var(--sidebar-text);
  font-size: 0.82rem;
  font-weight: 500;
  line-height: 1.45;
}

.backend-status::before {
  content: "";
  flex: 0 0 8px;
  width: 8px;
  height: 8px;
  margin-top: 5px;
  border-radius: 50%;
  background: var(--jacaranda);
}

.backend-status[data-state="online"]::before {
  background: var(--jacaranda);
  box-shadow: 0 0 0 3px rgba(143, 158, 201, 0.25);
}

.backend-status[data-state="offline"]::before {
  background: var(--accessible-ochre);
  box-shadow: 0 0 0 3px rgba(206, 61, 32, 0.2);
}

.backend-status[data-state="unknown"]::before {
  background: var(--jacaranda);
}

.sidebar-collapsed .backend-status {
  position: relative;
  display: block;
  width: 36px;
  height: 36px;
  margin: 0;
  padding: 0;
  border-radius: 9px;
  overflow: hidden;
  color: transparent;
  font-size: 0;
  line-height: 0;
}

.sidebar-collapsed .backend-status::before {
  position: absolute;
  top: 50%;
  left: 50%;
  transform: translate(-50%, -50%);
  width: 10px;
  height: 10px;
  margin: 0;
}

.sidebar-disclaimer {
  margin: 0;
  color: var(--sidebar-muted);
  font-size: 0.78rem;
  line-height: 1.5;
}

.sidebar-collapsed .sidebar-disclaimer {
  display: none;
}

.workspace {
  display: flex;
  flex-direction: column;
  gap: 18px;
  padding: 18px;
  min-width: 0;
}

.topbar {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 16px;
}

.topbar:empty {
  display: none;
}

.page-subtitle {
  margin: 4px 0 0;
  max-width: 760px;
  color: var(--muted);
  font-size: 0.95rem;
  line-height: 1.45;
}

.pipeline-flow {
  display: grid;
  gap: 0;
}

.pipeline-step {
  display: block;
  min-width: 0;
  padding: 16px 0;
  border-top: 1px solid var(--line);
}

.pipeline-step:first-child {
  padding-top: 0;
  border-top: 0;
}

.pipeline-step:last-child {
  padding-bottom: 0;
}

.pipeline-step h4 {
  margin: 0;
  color: var(--ink);
  font-size: 0.98rem;
  font-weight: 600;
  line-height: 1.25;
}

.pipeline-step p,
.pipeline-list,
.pipeline-data-list {
  margin: 8px 0 0 18px;
  color: var(--charcoal);
  font-size: 0.9rem;
  line-height: 1.45;
}

.pipeline-list,
.pipeline-data-list {
  display: grid;
  gap: 6px;
  padding-left: 18px;
}

.pipeline-data-list li {
  display: list-item;
  padding-left: 2px;
}

.pipeline-data-list span,
.pipeline-list li {
  color: var(--charcoal);
  font-weight: 500;
}

.pipeline-data-list span {
  display: inline;
}

.pipeline-data-list em {
  display: inline;
  margin-top: 0;
  color: var(--muted);
  font-style: normal;
  overflow-wrap: anywhere;
}

.pipeline-data-list em::before {
  content: none;
}

.pipeline-compact {
  color: var(--muted);
}

.classification-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 14px;
}

.classification-panel-inline {
  margin-top: 16px;
  padding-top: 16px;
  border-top: 1px solid var(--line);
}

.classification-inline-heading {
  margin-bottom: 14px;
}

.classification-card {
  display: grid;
  gap: 12px;
  min-width: 0;
  padding: 14px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: #ffffff;
}

.classification-card-top {
  display: flex;
  align-items: flex-start;
  justify-content: space-between;
  gap: 12px;
}

.classification-card-top span {
  min-width: 0;
  color: var(--charcoal);
  font-size: 0.86rem;
  font-weight: 850;
  line-height: 1.25;
}

.classification-card-top strong {
  flex: 0 0 auto;
  color: var(--ink);
  font-size: 1.35rem;
  line-height: 1;
}

.classification-status {
  display: flex;
  align-items: center;
  justify-content: flex-start;
  gap: 10px;
  min-width: 0;
}

.classification-status span {
  font-size: 0.76rem;
  font-style: normal;
  font-weight: 850;
  line-height: 1.25;
}

.classification-track {
  position: relative;
  height: 22px;
  margin: 34px 0 38px;
  border: 1px solid var(--line);
  border-radius: 999px;
  background:
    linear-gradient(
      90deg,
      rgba(143, 158, 201, 0.72) 0%,
      rgba(143, 158, 201, 0.72) var(--low-cutoff),
      rgba(218, 168, 162, 0.78) var(--low-cutoff),
      rgba(218, 168, 162, 0.78) var(--high-cutoff),
      rgba(230, 70, 38, 0.92) var(--high-cutoff),
      rgba(230, 70, 38, 0.92) 100%
    );
  overflow: visible;
}

.classification-band-label {
  position: absolute;
  top: 50%;
  z-index: 1;
  color: rgba(35, 42, 58, 0.72);
  font-size: 0.56rem;
  font-weight: 850;
  letter-spacing: 0;
  line-height: 1;
  pointer-events: none;
  text-transform: uppercase;
  transform: translate(-50%, -50%);
}

.classification-band-low {
  left: 12.5%;
}

.classification-band-mid {
  left: 50%;
}

.classification-band-high {
  left: 87.5%;
  color: rgba(255, 255, 255, 0.94);
}

.classification-cutoff-marker {
  position: absolute;
  top: -13px;
  bottom: -13px;
  left: var(--cutoff);
  width: 0;
  z-index: 1;
}

.classification-cutoff-line {
  position: absolute;
  top: 0;
  bottom: 0;
  left: 0;
  border-left: 2px solid rgba(0, 0, 0, 0.34);
  transform: translateX(-1px);
}

.classification-cutoff-badge {
  position: absolute;
  left: 0;
  display: inline-flex;
  align-items: center;
  min-height: 18px;
  padding: 2px 6px;
  border: 1px solid var(--line);
  border-radius: 999px;
  background: #ffffff;
  color: var(--charcoal);
  font-size: 0.62rem;
  font-weight: 850;
  line-height: 1;
  white-space: nowrap;
  transform: translateX(-50%);
}

.classification-cutoff-low .classification-cutoff-badge,
.classification-cutoff-high .classification-cutoff-badge {
  top: calc(100% + 4px);
}

.classification-cutoff-marker.is-right-edge .classification-cutoff-badge {
  transform: translateX(-100%);
}

.classification-cutoff-marker.is-left-edge .classification-cutoff-badge {
  transform: translateX(0);
}

.classification-score-marker {
  position: absolute;
  top: 50%;
  left: var(--score);
  width: 15px;
  height: 15px;
  border: 2px solid #ffffff;
  border-radius: 999px;
  background: transparent;
  box-shadow: 0 0 0 1px rgba(0, 0, 0, 0.18);
  transform: translate(-50%, -50%);
  z-index: 3;
}

.classification-score-marker::before {
  content: "";
  position: absolute;
  inset: 1px;
  border-radius: inherit;
  background: currentColor;
  opacity: 0.68;
}

.classification-score-marker i {
  position: absolute;
  bottom: calc(100% + 6px);
  left: 50%;
  padding: 3px 6px;
  border: 1px solid var(--line);
  border-radius: 999px;
  background: #ffffff;
  color: var(--ink);
  font-size: 0.68rem;
  font-style: normal;
  font-weight: 850;
  line-height: 1;
  white-space: nowrap;
  transform: translateX(-50%);
}

.classification-score-marker.is-right-edge i {
  transform: translateX(-100%);
}

.classification-score-marker.is-left-edge i {
  transform: translateX(0);
}

#methods > .panel + .panel,
#methods > .panel + .biomarker-grid,
#methods > .biomarker-grid + .panel {
  margin-top: 18px;
}

#methods > .biomarker-grid:first-child {
  margin-top: 0;
}

.credits-grid {
  display: grid;
  grid-template-columns: 1fr;
  gap: 18px;
  margin-top: 0;
}

#references > .panel + .panel,
#references > .panel + .credits-grid,
#references > .credits-grid + .panel {
  margin-top: 18px;
}

.team-list {
  display: grid;
  gap: 0;
  margin-top: 8px;
}

.acknowledgment-list {
  display: grid;
  gap: 12px;
  margin-top: 14px;
}

.member-row {
  display: grid;
  gap: 6px;
  padding: 10px 0;
  border-top: 1px solid var(--line);
  background: transparent;
  color: var(--charcoal);
  font-size: 0.95rem;
  line-height: 1.5;
}

.member-heading {
  display: flex;
  align-items: baseline;
  gap: 8px;
  min-width: 0;
}

.member-name {
  font-family: var(--font-sans);
  color: var(--ink);
  font-size: 18px;
  font-weight: 500;
  letter-spacing: 0;
  line-height: 1.04;
  white-space: nowrap;
}

.member-name::after {
  content: "|";
  margin-left: 8px;
  color: var(--muted);
  font-weight: 400;
}

.member-role {
  min-width: 0;
  color: var(--muted);
  font-size: 0.9rem;
  font-weight: 400;
  line-height: 1.45;
}

.member-email,
.member-address,
.acknowledgment-list p {
  margin: 0;
  color: var(--charcoal);
  font-size: 0.9rem;
  line-height: 1.45;
}

.member-email {
  display: inline-flex;
  width: fit-content;
  color: var(--heritage-rose);
  font-weight: 700;
  overflow-wrap: anywhere;
  text-decoration: underline;
  text-decoration-thickness: 1px;
  text-underline-offset: 3px;
}

.member-email:hover {
  color: color-mix(in srgb, var(--heritage-rose) 78%, var(--ink));
  text-decoration-thickness: 2px;
}

.member-email-pending {
  color: var(--muted);
  font-weight: 400;
  text-decoration: none;
}

.member-email-pending:hover {
  color: var(--muted);
  text-decoration: none;
}

.member-address {
  color: var(--muted);
}

.reference-list {
  display: grid;
  gap: 12px;
  margin: 14px 0 0;
  padding-left: 22px;
}

.reference-list li {
  color: var(--charcoal);
  font-size: 0.9rem;
  line-height: 1.5;
  scroll-margin-top: 28px;
  transition:
    background 180ms ease,
    box-shadow 180ms ease;
}

.reference-list li.reference-focus {
  border-radius: 7px;
  background: rgba(206, 61, 32, 0.1);
  box-shadow: 0 0 0 5px rgba(206, 61, 32, 0.1);
}

.reference-list a {
  color: var(--ochre);
  font-weight: 400;
  overflow-wrap: anywhere;
}

.reference-list a:hover {
  color: var(--accessible-ochre);
  text-decoration-thickness: 2px;
}

.citation-link {
  color: var(--primary);
  font-weight: 600;
  text-decoration: underline;
  text-decoration-thickness: 1px;
  text-underline-offset: 3px;
}

.citation-link:hover {
  color: var(--primary-hover);
  text-decoration-thickness: 2px;
}

.section-link {
  color: var(--ochre);
  font-weight: 600;
  text-decoration: underline;
  text-decoration-thickness: 1px;
  text-underline-offset: 3px;
}

.section-link:hover {
  color: var(--accessible-ochre);
  text-decoration-thickness: 2px;
}

.status-cluster {
  display: inline-flex;
  align-items: center;
  gap: 8px;
  min-height: 36px;
  padding: 0 12px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--surface);
  color: var(--muted);
  font-size: 0.9rem;
}

.status-dot {
  width: 9px;
  height: 9px;
  border-radius: 99px;
  background: var(--stability-accent);
}

.tab-panel {
  display: none;
}

.tab-panel.active {
  display: block;
}

.calculator-grid {
  display: grid;
  grid-template-columns: minmax(0, 48fr) minmax(0, 52fr);
  gap: 18px;
  align-items: stretch;
}

.lower-grid,
.summary-grid,
.biomarker-grid {
  display: grid;
  gap: 18px;
  margin-top: 18px;
}

.summary-integrated {
  margin-top: 18px;
}

.lower-grid {
  grid-template-columns: repeat(3, minmax(0, 1fr));
  align-items: stretch;
}

.lower-grid.lower-grid-two {
  grid-template-columns: repeat(2, minmax(0, 1fr));
}

.lower-grid.lower-grid-one,
.summary-grid.summary-grid-one {
  grid-template-columns: 1fr;
}

.summary-grid,
.biomarker-grid {
  align-items: stretch;
}

.summary-grid {
  grid-template-columns: repeat(2, minmax(0, 1fr));
}

.biomarker-grid {
  grid-template-columns: repeat(2, minmax(0, 1fr));
  align-items: start;
  overflow-x: visible;
  padding-bottom: 0;
}

.panel {
  min-width: 0;
  padding: 18px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--surface);
  box-shadow: var(--shadow);
}

.calculator-grid > .panel {
  height: var(--calculator-panel-height, auto);
  min-height: 0;
  overflow: hidden;
}

.calculator-section {
  margin-top: 18px;
  padding-top: 10px;
  border-top: 1px solid var(--line);
}

.calculator-section .calculator-card-header {
  align-items: center;
  margin-bottom: 10px;
}

.calculator-section .calculator-card-header h3 {
  margin: 0;
  color: var(--muted);
  font-size: 1rem;
  font-weight: 400;
  line-height: 1.35;
}

.calculator-section .summary-note {
  margin-top: 0;
}

.handoff-section {
  margin-bottom: 22px;
}

.calculator-header-actions {
  display: flex;
  flex: 0 0 auto;
  flex-wrap: wrap;
  justify-content: flex-end;
  gap: 8px;
}

.wide-panel {
  margin-top: 0;
}

.panel-heading {
  display: flex;
  align-items: flex-start;
  justify-content: space-between;
  gap: 16px;
  margin-bottom: 22px;
}

.compact-heading {
  margin-bottom: 22px;
}

.panel-heading > div {
  min-width: 0;
}

.panel-heading h3,
.panel > h3:first-child {
  font-size: 1.35rem;
  line-height: 1.2;
  letter-spacing: 0;
  white-space: nowrap;
}

.panel-heading h3 {
  margin: 4px 0 8px;
}

.panel > h3:first-child {
  margin: 4px 0 22px;
}

.panel-heading .subnav {
  justify-content: flex-end;
  margin-bottom: 0;
}

select,
.primary-button,
.secondary-button,
.icon-button,
.subnav-button,
.step-button,
.segment {
  min-height: 34px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: #ffffff;
  color: var(--ink);
}

select {
  max-width: 220px;
  padding: 0 34px 0 12px;
}

.primary-button,
.secondary-button,
.icon-button,
.subnav-button,
.step-button {
  padding: 0 12px;
}

.primary-button {
  border-color: var(--primary);
  background: var(--primary);
  color: #ffffff;
  font-weight: 800;
}

.primary-button:hover {
  background: var(--primary-hover);
}

.secondary-button {
  color: var(--charcoal);
}

.secondary-button:hover {
  border-color: var(--charcoal);
  background: var(--light-grey);
}

.icon-button {
  display: grid;
  width: 34px;
  padding: 0;
  place-items: center;
  color: var(--charcoal);
}

.icon-button:hover {
  border-color: var(--charcoal);
  background: var(--light-grey);
}

.segmented {
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  gap: 6px;
  margin-bottom: 18px;
  padding: 4px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--light-grey);
}

.segment {
  border-color: transparent;
  background: transparent;
}

.segment.active {
  color: #ffffff;
  background: var(--primary);
}

.segment.disabled {
  color: var(--muted);
  cursor: not-allowed;
}

.action-row {
  display: flex;
  gap: 10px;
  margin-top: 18px;
}

.action-row button {
  flex: 1;
}

.subnav {
  display: flex;
  flex-wrap: wrap;
  gap: 6px;
  margin-bottom: 14px;
}

.compact-subnav {
  margin-bottom: 0;
}

.subnav-button,
.step-button {
  background: #ffffff;
  color: var(--charcoal);
  font-size: 0.86rem;
}

.subnav-button:hover,
.step-button:hover {
  border-color: var(--charcoal);
}

.subnav-button.active,
.step-button.active {
  border-color: var(--primary);
  background: var(--primary-soft);
  color: var(--primary);
  font-weight: 800;
}

.field-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 14px;
}

.field {
  display: grid;
  grid-template-columns: 1fr auto;
  gap: 8px 12px;
  align-items: center;
  min-height: 76px;
  padding: 12px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: #ffffff;
}

.field span {
  color: var(--charcoal);
  font-weight: 700;
}

.field output {
  min-width: 36px;
  padding: 2px 8px;
  border-radius: 8px;
  background: var(--primary-soft);
  color: var(--primary);
  text-align: center;
  font-weight: 800;
}

.field input {
  grid-column: 1 / -1;
  width: 100%;
  accent-color: var(--primary);
}

.field-number {
  min-height: auto;
  grid-template-columns: 1fr;
  align-items: start;
}

.field-number input[type="number"] {
  padding: 8px 10px;
  border: 1px solid var(--line);
  border-radius: 6px;
  font: inherit;
  background: #fff;
}

.field-compact {
  min-height: auto;
  padding: 8px;
}

.field-compact span {
  font-size: 0.78rem;
  font-weight: 600;
  word-break: break-word;
}

.field-grid-dense {
  grid-template-columns: repeat(auto-fill, minmax(148px, 1fr));
  gap: 10px;
  max-height: 280px;
  overflow-y: auto;
  padding: 4px 2px 8px;
}

.model-input-panels {
  margin-top: 14px;
}

.model-input-panel {
  display: none;
  padding: 12px 0 0;
}

.model-input-panel.active {
  display: block;
}

.model-input-panel[hidden] {
  display: none !important;
}

.select-field-panel {
  display: grid;
  grid-template-columns: 1fr;
  gap: 8px;
  margin-bottom: 12px;
  padding: 12px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: #fff;
}

.select-field-panel select {
  width: 100%;
}

.panel-actions {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 10px;
}

.panel-actions select {
  min-width: 160px;
}

.model-section-actions {
  margin-top: 12px;
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 12px;
}

.file-box-inline {
  display: block;
  margin: 12px 0 0;
  padding: 12px;
  border: 1px dashed var(--line);
  border-radius: 8px;
  background: #fff;
}

/* CSV upload panel */
.csv-panel {
  display: flex;
  flex-direction: column;
  gap: 0;
  height: 100%;
  min-height: 0;
}

.result-panel {
  display: flex;
  flex-direction: column;
  height: 100%;
  min-height: 0;
}

.csv-panel-header,
.calculator-card-header {
  margin-bottom: 22px;
}

.csv-panel-header h3,
.calculator-card-header h3 {
  margin: 4px 0 8px;
  font-size: 1.35rem;
  line-height: 1.2;
  letter-spacing: 0;
  white-space: nowrap;
}

.calculator-card-header {
  display: flex;
  align-items: flex-start;
  justify-content: space-between;
  gap: 16px;
}

.csv-upload-intro {
  margin: 0;
  max-width: 42ch;
  color: var(--charcoal);
  font-size: 0.92rem;
  line-height: 1.55;
}

.csv-dropzone {
  display: flex;
  margin: 0;
  min-height: 220px;
  padding: 28px 20px;
  border: 2px dashed #c8c8c8;
  border-radius: 12px;
  background: #ffffff;
  cursor: pointer;
  transition:
    border-color 160ms ease,
    background 160ms ease,
    box-shadow 160ms ease;
}

.csv-dropzone:hover,
.csv-dropzone.is-dragover {
  border-color: var(--primary);
  background: #ffffff;
  box-shadow: 0 0 0 4px rgba(206, 61, 32, 0.1);
}

.csv-dropzone:focus-within {
  border-color: var(--primary);
  box-shadow: 0 0 0 4px rgba(206, 61, 32, 0.14);
}

.csv-dropzone.is-loaded {
  border-color: var(--ochre);
  border-style: solid;
  background: #ffffff;
  box-shadow: 0 0 0 4px rgba(230, 70, 38, 0.1);
}

.csv-dropzone-inner,
.csv-dropzone {
  flex-direction: column;
  align-items: center;
  justify-content: center;
  text-align: center;
  gap: 8px;
}

.csv-dropzone-icon {
  display: grid;
  width: 52px;
  height: 52px;
  place-items: center;
  border-radius: 999px;
  background: #ffffff;
  color: var(--primary);
  box-shadow: 0 4px 14px rgba(0, 0, 0, 0.06);
}

.csv-dropzone-title {
  font-size: 0.98rem;
  font-weight: 700;
  color: var(--ink);
}

.csv-dropzone-file {
  max-width: 100%;
  padding: 4px 12px;
  border-radius: 999px;
  background: rgba(255, 255, 255, 0.9);
  color: var(--navy);
  font-size: 0.86rem;
  font-weight: 700;
  word-break: break-all;
}

.csv-dropzone-file.is-loaded {
  background: var(--primary-soft);
  color: var(--primary);
}

.csv-dropzone-hint {
  color: var(--charcoal);
  font-size: 0.82rem;
}

.csv-dropzone-hint kbd {
  display: inline-block;
  margin: 0 2px;
  padding: 2px 7px;
  border: 1px solid var(--line);
  border-radius: 6px;
  background: #ffffff;
  font-family: var(--font-mono);
  font-size: 0.78rem;
  font-weight: 600;
}

.csv-panel-divider {
  margin-top: 18px;
  border-top: 1px solid var(--line);
}

.csv-extraction-summary {
  margin-top: 10px;
  padding: 0;
  border: 0;
  border-radius: 0;
  background: transparent;
}

.csv-extraction-summary.csv-extraction-idle {
  background: transparent;
}

.csv-idle-text {
  margin: 0;
  color: var(--charcoal);
  font-size: 0.9rem;
}

.csv-extraction-summary.csv-extraction-idle .csv-idle-text {
  color: var(--accessible-ochre);
  font-weight: 700;
}

.csv-section-head {
  margin-bottom: 12px;
}

.csv-model-cards {
  display: grid;
  gap: 8px;
}

.csv-model-card {
  appearance: none;
  display: flex;
  flex-direction: column;
  justify-content: center;
  width: 100%;
  min-height: 64px;
  padding: 10px 12px;
  border: 1px solid color-mix(in srgb, var(--navy) 58%, transparent);
  border-radius: 8px;
  background: #ffffff;
  color: inherit;
  cursor: pointer;
  font: inherit;
  text-align: left;
  transition: background 150ms ease, border-color 150ms ease, box-shadow 150ms ease;
}

.csv-model-card.is-complete {
  border-color: color-mix(in srgb, var(--navy) 70%, transparent);
  background: #ffffff;
}

.csv-model-card.is-partial {
  border-color: color-mix(in srgb, var(--navy) 58%, transparent);
  background: #ffffff;
}

.csv-model-card.is-waiting {
  border-style: dashed;
  background: #ffffff;
}

.csv-model-card:hover,
.csv-model-card:focus-visible {
  border-color: var(--navy);
  background: color-mix(in srgb, var(--jacaranda) 16%, transparent);
  box-shadow: inset 0 0 0 1px color-mix(in srgb, var(--navy) 30%, transparent);
  outline: 0;
}

.csv-model-card.active {
  border-color: var(--navy);
  background: color-mix(in srgb, var(--jacaranda) 28%, transparent);
  box-shadow: inset 0 0 0 1px color-mix(in srgb, var(--navy) 40%, transparent);
  outline: 0;
}

.csv-model-card-top {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 10px;
  margin-bottom: 6px;
}

.csv-model-card-label {
  font-size: 0.88rem;
  font-weight: 400;
  color: var(--ink);
}

.csv-model-card-fraction {
  font-size: 0.82rem;
  font-weight: 400;
  color: var(--charcoal);
}

.csv-model-card-bar {
  display: block;
  height: 5px;
  overflow: hidden;
  border-radius: 999px;
  background: var(--light-grey);
}

.csv-model-card-bar span {
  display: block;
  height: 100%;
  border-radius: inherit;
  background: var(--jacaranda);
  transition: width 320ms ease;
}

.csv-model-card.is-partial .csv-model-card-bar span {
  background: var(--ochre);
}

.csv-model-card.is-waiting .csv-model-card-fraction {
  color: var(--muted);
}

.csv-model-card.is-waiting .csv-model-card-bar span {
  width: 0;
}

.csv-model-card-note {
  display: block;
  margin: 6px 0 0;
  font-size: 0.78rem;
  color: var(--primary);
}

.csv-unknown {
  margin: 12px 0 0;
  padding-top: 12px;
  border-top: 1px solid var(--line);
  color: var(--charcoal);
  font-size: 0.82rem;
  line-height: 1.45;
}

.csv-model-results {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 10px;
  margin-top: 14px;
}

.risk-tier-footnote {
  grid-column: 1 / -1;
  margin: 4px 0 0;
  color: var(--muted);
  font-size: 0.78rem;
  line-height: 1.4;
}

.csv-result-tile {
  padding: 14px 12px;
  border: 1px solid var(--line);
  border-radius: 10px;
  background: #ffffff;
  text-align: center;
}

.csv-result-tile.is-diagnosis {
  border-top: 3px solid var(--navy);
}

.csv-result-tile.is-progression {
  border-top: 3px solid var(--primary);
}

.csv-result-tile.is-response {
  border-top: 3px solid var(--jacaranda);
}

.csv-result-tile-label {
  display: block;
  margin-bottom: 6px;
  color: var(--charcoal);
  font-size: 0.72rem;
  font-weight: 800;
  letter-spacing: 0.04em;
  text-transform: uppercase;
}

.csv-result-tile-value {
  display: block;
  font-size: 1.45rem;
  font-weight: 800;
  line-height: 1.1;
  color: var(--ink);
}

.csv-result-tile-meta {
  display: block;
  margin-top: 4px;
  color: var(--charcoal);
  font-size: 0.75rem;
}

.csv-result-tile-tier,
.model-output-tier {
  display: block;
  margin-top: 6px;
  font-size: 0.72rem;
  font-weight: 800;
  font-style: normal;
  white-space: nowrap;
}

.risk-tier-low {
  color: var(--risk-low);
}

.risk-tier-intermediate {
  color: var(--risk-moderate);
}

.risk-tier-high {
  color: var(--risk-high);
}

.risk-tier-unknown {
  color: var(--muted);
  font-weight: 600;
}

.clinical-action-list {
  display: grid;
  gap: 8px;
}

.clinical-review-actions {
  margin-top: 0;
  padding-top: 2px;
}

.clinical-action-line {
  appearance: none;
  display: flex;
  align-items: center;
  width: 100%;
  min-height: 64px;
  padding: 10px 12px;
  border: 1px solid color-mix(in srgb, var(--navy) 58%, transparent);
  border-radius: 8px;
  background: #ffffff;
  color: var(--charcoal);
  cursor: pointer;
  font: inherit;
  font-size: 0.88rem;
  line-height: 1.45;
  text-align: left;
  transition: border-color 150ms ease, box-shadow 150ms ease, background 150ms ease;
}

.clinical-action-line:hover,
.clinical-action-line:focus-visible {
  border-color: var(--navy);
  background: color-mix(in srgb, var(--jacaranda) 16%, transparent);
  box-shadow: inset 0 0 0 1px color-mix(in srgb, var(--navy) 30%, transparent);
  outline: 0;
}

.clinical-action-line.active {
  border-color: var(--navy);
  background: color-mix(in srgb, var(--jacaranda) 28%, transparent);
  box-shadow: inset 0 0 0 1px color-mix(in srgb, var(--navy) 40%, transparent);
}

.clinical-action-line.is-empty {
  border-style: dashed;
  background: #ffffff;
  box-shadow: none;
}

.clinical-action-line.is-empty:hover,
.clinical-action-line.is-empty:focus-visible {
  border-color: var(--navy);
  background: color-mix(in srgb, var(--jacaranda) 16%, transparent);
  box-shadow: inset 0 0 0 1px color-mix(in srgb, var(--navy) 30%, transparent);
}

.clinical-action-top {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 10px;
  margin-bottom: 6px;
}

.clinical-action-label {
  color: var(--ink);
  font-size: 0.88rem;
  font-weight: 400;
}

.clinical-action-meta {
  color: var(--charcoal);
  font-size: 0.82rem;
  font-weight: 400;
  white-space: nowrap;
}

.clinical-action-text {
  display: block;
  color: var(--charcoal);
  font-size: 0.88rem;
  line-height: 1.45;
}

.clinical-action-bar {
  display: block;
  height: 5px;
  overflow: hidden;
  border-radius: 999px;
  background: var(--light-grey);
}

.clinical-action-bar span {
  display: block;
  width: 0;
  height: 100%;
  border-radius: inherit;
  background: var(--jacaranda);
}

.clinical-action-disclaimer {
  margin: 14px 0 0;
  padding-top: 12px;
  border-top: 1px solid var(--line);
  color: var(--muted);
  font-size: 0.88rem;
  font-style: italic;
  line-height: 1.45;
}

.right-panel-warning {
  margin-top: auto;
}

.right-panel-warning:empty,
.right-panel-warning[hidden] {
  display: none;
}

.run-models-row {
  margin-top: 16px;
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 12px;
}

.input-status {
  margin: 0;
  color: var(--muted);
  font-size: 0.9rem;
}

.primary-button:disabled {
  opacity: 0.65;
  cursor: not-allowed;
}

.awaiting-run,
.run-summary {
  color: var(--muted);
  font-size: 0.92rem;
  line-height: 1.5;
}

.run-summary p {
  margin: 0 0 8px;
}

.input-section-label {
  margin-bottom: 6px;
}

.select-field {
  grid-column: 1 / -1;
}

.select-field select {
  grid-column: 1 / -1;
  width: 100%;
  max-width: none;
}

.upload-strip {
  display: grid;
  grid-template-columns: 1fr auto;
  gap: 12px;
  align-items: stretch;
  margin-top: 16px;
}

.file-box {
  display: grid;
  gap: 4px;
  padding: 10px 12px;
  border: 1px dashed var(--charcoal);
  border-radius: 8px;
  background: #ffffff;
}

.file-box input {
  display: none;
}

#upload-name:not(.is-loaded) {
  color: var(--muted);
  font-weight: 600;
}

.model-chip {
  padding: 5px 10px;
  border-radius: 999px;
  background: var(--primary-soft);
  color: var(--analysis-accent);
  font-size: 0.82rem;
  font-weight: 800;
}

.risk-visual {
  display: grid;
  grid-template-columns: 230px 1fr;
  gap: 26px;
  align-items: center;
}

.risk-ring {
  --risk: 48%;
  display: grid;
  width: 230px;
  height: 230px;
  place-items: center;
  border-radius: 50%;
  background:
    radial-gradient(circle at center, #ffffff 0 58%, transparent 59%),
    conic-gradient(var(--primary) var(--risk), var(--light-grey) 0);
}

.risk-ring span {
  font-size: 2.8rem;
  font-weight: 850;
}

.risk-copy {
  min-width: 0;
}

.risk-copy p {
  margin-bottom: 18px;
  color: var(--charcoal);
  font-size: 1rem;
  line-height: 1.5;
}

.model-output-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 10px;
  margin-top: 0;
}

.model-output-tile {
  display: grid;
  grid-template-rows: 34px 86px minmax(30px, auto) 20px;
  justify-items: center;
  align-content: start;
  gap: 8px 12px;
  min-height: 204px;
  padding: 12px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: #ffffff;
  text-align: center;
  --output-color: var(--muted);
  --output-risk: 0%;
}

.note-line {
  border-color: var(--primary);
  background: var(--primary-soft);
  color: var(--charcoal);
}

.model-output-tile:hover,
.model-output-tile.active {
  border-color: var(--primary);
  background: var(--primary-soft);
}

.model-output-label {
  justify-self: start;
  min-height: 34px;
  color: var(--muted);
  font-size: 0.78rem;
  font-weight: 800;
  line-height: 1.25;
  text-align: left;
  text-transform: uppercase;
}

.model-output-stat {
  display: grid;
  width: 86px;
  height: 86px;
  place-items: center;
  border-radius: 50%;
  background:
    radial-gradient(circle at center, #ffffff 0 56%, transparent 57%),
    conic-gradient(var(--output-color) var(--output-risk), var(--light-grey) 0);
  color: var(--ink);
  line-height: 1;
}

.model-output-stat span {
  font-size: 1.24rem;
  font-weight: 850;
}

.model-output-description {
  max-width: 18ch;
  color: var(--charcoal);
  font-size: 0.82rem;
  font-weight: 700;
  line-height: 1.25;
}

.model-output-tile .model-output-tier {
  margin-top: 0;
  line-height: 1.12;
  white-space: normal;
}

.model-output-tier span {
  display: block;
}

.confidence-row {
  display: flex;
  flex-direction: column;
  justify-content: center;
  gap: 8px;
  color: var(--muted);
}

.confidence-row span {
  font-size: 1rem;
}

.sparkline-heading {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 12px;
  color: var(--muted);
}

.sparkline-title-group {
  display: flex;
  align-items: baseline;
  gap: 10px;
  min-width: 0;
}

.sparkline-heading span {
  color: var(--muted);
  font-size: 1rem;
  font-weight: 400;
  line-height: 1.35;
}

.confidence-row strong,
.sparkline-heading strong {
  color: var(--ink);
}

.ifn-status {
  font-weight: 850;
}

.ifn-status-high {
  color: var(--risk-high);
}

.ifn-status-neutral {
  color: var(--risk-moderate);
}

.ifn-status-low {
  color: var(--risk-low);
}

.ifn-status-empty {
  color: var(--muted);
}

.confidence-row strong {
  font-size: 1.45rem;
  line-height: 1.12;
}

.sparkline-panel {
  margin-top: 18px;
  padding-top: 10px;
  border-top: 1px solid var(--line);
}

.fingerprint-chart-box {
  margin-top: 0;
  padding: 0;
  border: 0;
  border-radius: 0;
  background: transparent;
  overflow: visible;
}

.fingerprint-scroll {
  overflow-x: scroll;
  overflow-y: visible;
  padding: 0 10px 14px;
  scrollbar-color: var(--charcoal) transparent;
  scrollbar-gutter: stable;
  scrollbar-width: thin;
}

.fingerprint-scroll::-webkit-scrollbar {
  height: 8px;
}

.fingerprint-scroll::-webkit-scrollbar-track {
  background: transparent;
}

.fingerprint-scroll::-webkit-scrollbar-thumb {
  border: 2px solid #ffffff;
  border-radius: 999px;
  background: var(--charcoal);
}

.fingerprint {
  display: grid;
  grid-template-columns: repeat(var(--fingerprint-count, 18), minmax(16px, 1fr));
  gap: 4px;
  height: 102px;
  min-width: max(100%, var(--fingerprint-min-width, 0px));
  margin-top: 0;
  padding-top: 32px;
  overflow: visible;
}

.fingerprint-cell {
  --bar-color: var(--signal-neutral);
  --bar-tag-text: #000000;
  appearance: none;
  position: relative;
  padding: 0;
  cursor: pointer;
  min-width: 0;
  border: 1px solid rgba(0, 0, 0, 0.08);
  border-radius: 5px;
  background: var(--bar-color);
  transition: background 140ms ease, border-color 140ms ease, box-shadow 140ms ease, transform 140ms ease;
}

.fingerprint-cell .bar-hover-tag {
  top: -25px;
}

.fingerprint-cell:not(.is-empty):hover,
.fingerprint-cell:not(.is-empty):focus-visible {
  border-color: var(--bar-color);
  box-shadow:
    0 0 0 4px color-mix(in srgb, var(--bar-color) 36%, transparent),
    0 12px 18px color-mix(in srgb, var(--bar-color) 24%, transparent);
  outline: 0;
  transform: translateY(-3px);
}

.fingerprint-cell.is-empty {
  border-color: var(--line);
  background: #ffffff;
  cursor: default;
}

.fingerprint-cell.is-empty:hover {
  border-color: var(--navy);
  background: color-mix(in srgb, var(--jacaranda) 16%, transparent);
  box-shadow:
    inset 0 0 0 1px color-mix(in srgb, var(--navy) 30%, transparent),
    0 8px 14px color-mix(in srgb, var(--jacaranda) 18%, transparent);
  transform: translateY(-2px);
}

.signal-high-strong {
  --bar-color: var(--signal-high);
  --bar-tag-text: #ffffff;
  background: var(--bar-color);
}

.signal-high {
  --bar-color: var(--signal-high-soft);
  --bar-tag-text: #000000;
  background: var(--bar-color);
}

.signal-neutral {
  --bar-color: var(--signal-neutral);
  --bar-tag-text: #000000;
  background: var(--bar-color);
}

.signal-low {
  --bar-color: var(--signal-low-soft);
  --bar-tag-text: #000000;
  background: var(--bar-color);
}

.signal-low-strong {
  --bar-color: var(--signal-low);
  --bar-tag-text: #ffffff;
  background: var(--bar-color);
}

.bar-hover-tag {
  --tag-translate-x: -50%;
  position: absolute;
  top: -21px;
  left: 50%;
  z-index: 5;
  max-width: min(18ch, 160px);
  padding: 3px 6px;
  border: 1px solid color-mix(in srgb, var(--bar-color) 72%, #000000);
  border-radius: 999px;
  background: var(--bar-color);
  box-shadow: 0 8px 18px rgba(0, 0, 0, 0.16);
  color: var(--bar-tag-text);
  font-size: 0.64rem;
  font-weight: 850;
  line-height: 1;
  opacity: 0;
  overflow-x: auto;
  overflow-y: hidden;
  pointer-events: none;
  scrollbar-width: thin;
  text-overflow: clip;
  transform: translate(var(--tag-translate-x), 6px);
  transition: opacity 140ms ease, transform 140ms ease;
  white-space: nowrap;
}

.bar-hover-tag::-webkit-scrollbar {
  height: 4px;
}

.bar-hover-tag::-webkit-scrollbar-track {
  background: transparent;
}

.bar-hover-tag::-webkit-scrollbar-thumb {
  border-radius: 999px;
  background: color-mix(in srgb, var(--bar-tag-text) 44%, transparent);
}

.fingerprint-cell:nth-child(-n + 2) .bar-hover-tag,
.heatmap-item:nth-child(-n + 2) .bar-hover-tag {
  --tag-translate-x: 0;
  left: 0;
}

.fingerprint-cell:nth-last-child(-n + 2) .bar-hover-tag,
.heatmap-item:nth-last-child(-n + 2) .bar-hover-tag {
  --tag-translate-x: 0;
  right: 0;
  left: auto;
}

.fingerprint-cell:not(.is-empty):hover .bar-hover-tag,
.fingerprint-cell:not(.is-empty):focus-visible .bar-hover-tag,
.heatmap-item:hover .bar-hover-tag,
.heatmap-item:focus-visible .bar-hover-tag {
  opacity: 1;
  pointer-events: auto;
  transform: translate(var(--tag-translate-x), 0);
}

.fingerprint-legend,
.driver-legend,
.metric-legend,
.heatmap-legend {
  display: flex;
  flex-wrap: wrap;
  gap: 10px 14px;
  color: var(--muted);
  font-size: 0.78rem;
  font-weight: 700;
}

.fingerprint-legend {
  justify-content: flex-end;
  margin-top: 8px;
  text-align: right;
}

.driver-legend {
  justify-content: flex-end;
  margin-top: 10px;
  text-align: right;
}

.fingerprint-legend span,
.driver-legend span,
.metric-legend span,
.heatmap-legend span {
  display: inline-flex;
  align-items: center;
  gap: 6px;
}

.fingerprint-legend i,
.driver-legend i,
.metric-legend i,
.heatmap-legend i {
  display: block;
  width: 12px;
  flex: 0 0 12px;
  height: 12px;
  border: 1px solid rgba(0, 0, 0, 0.1);
  border-radius: 4px;
}

.driver-legend i {
  background: var(--driver-color, var(--primary));
}

.fingerprint-drivers {
  display: flex;
  flex: 1 1 0;
  flex-direction: column;
  margin-top: 18px;
  min-height: 0;
  padding: 14px 0 12px;
  border-top: 1px solid var(--line);
  background: transparent;
}

.driver-heading {
  margin: 0 0 10px;
}

.sparkline-heading .driver-mode-indicator {
  flex: 0 0 auto;
  max-width: 100%;
  padding: 4px 9px;
  border: 1px solid var(--navy);
  border-radius: 7px;
  background: color-mix(in srgb, var(--jacaranda) 28%, transparent);
  color: var(--ink);
  font-size: 0.88rem;
  font-weight: 400;
  line-height: 1.2;
  overflow: hidden;
  text-overflow: ellipsis;
  white-space: nowrap;
}

.sparkline-heading .driver-mode-indicator.is-empty {
  width: 0;
  min-width: 0;
  padding: 0;
  border: 0;
  background: transparent;
}

.driver-actions {
  display: flex;
  flex-wrap: wrap;
  justify-content: flex-end;
  gap: 8px;
}

.molecular-heading .driver-actions {
  flex: 0 0 auto;
}

.driver-actions .secondary-button {
  min-height: 30px;
  padding: 0 10px;
  font-size: 0.82rem;
  font-weight: 400;
}

.model-output-learn-more,
#copy-summary {
  min-height: 30px;
  padding: 0 10px;
  font-size: 0.82rem;
  font-weight: 400;
}

.handoff-heading {
  align-items: center;
}

.handoff-subnav {
  align-items: center;
  justify-content: flex-end;
  margin: 0;
}

.handoff-subnav .subnav-button {
  min-height: 30px;
  padding: 0 10px;
  font-size: 0.82rem;
}

.handoff-view-select {
  min-height: 30px;
  max-width: 170px;
  padding: 0 28px 0 10px;
  color: var(--charcoal);
  font-size: 0.82rem;
  font-weight: 400;
}

.gene-filter-select {
  min-height: 30px;
  max-width: 160px;
  padding: 0 30px 0 10px;
  color: var(--charcoal);
  font-size: 0.82rem;
  font-weight: 400;
}

.driver-list {
  position: relative;
  display: grid;
  align-content: start;
  flex: 1 1 0;
  gap: 8px;
  grid-auto-rows: min-content;
  min-height: 0;
  max-height: 100%;
  overflow-y: scroll;
  padding: 0 28px 0 0;
  border: 0;
  border-radius: 0;
  scrollbar-color: var(--charcoal) transparent;
  scrollbar-gutter: stable both-edges;
  scrollbar-width: thin;
}

.calculator-grid.is-empty .driver-list {
  flex: 0 0 auto;
  min-height: 124px;
  max-height: none;
}

.calculator-grid.is-empty .fingerprint-drivers {
  flex: 0 0 auto;
  padding-bottom: 22px;
}

.driver-list::-webkit-scrollbar {
  width: 8px;
}

.driver-list::-webkit-scrollbar-track {
  background: transparent;
}

.driver-list::-webkit-scrollbar-thumb {
  border: 2px solid #ffffff;
  border-radius: 999px;
  background: var(--charcoal);
}

.driver-row {
  appearance: none;
  display: grid;
  grid-template-columns: minmax(86px, 130px) minmax(128px, 1fr);
  gap: 8px;
  align-items: center;
  width: 100%;
  min-height: 36px;
  padding: 1px 0;
  border: 0;
  border-radius: 7px;
  background: transparent;
  color: inherit;
  cursor: pointer;
  font: inherit;
  text-align: left;
  transition: background 140ms ease;
}

.driver-row:hover,
.driver-row:focus-visible {
  background: transparent;
  outline: 0;
}

.driver-row:hover .bar-track,
.driver-row:focus-visible .bar-track {
  box-shadow: 0 0 0 3px color-mix(in srgb, var(--driver-color, var(--primary)) 24%, transparent);
}

.driver-row:hover .bar-fill,
.driver-row:focus-visible .bar-fill {
  filter: saturate(1.12);
}

.driver-row-empty {
  grid-template-columns: minmax(0, 1fr);
  color: var(--muted);
  cursor: default;
  opacity: 1;
}

.driver-row-empty:hover .bar-track,
.driver-row-empty:focus-visible .bar-track {
  border-color: var(--navy);
  background: color-mix(in srgb, var(--jacaranda) 16%, transparent);
  box-shadow: inset 0 0 0 1px color-mix(in srgb, var(--navy) 30%, transparent);
}

.driver-row-empty:hover .bar-fill,
.driver-row-empty:focus-visible .bar-fill {
  background: color-mix(in srgb, var(--jacaranda) 26%, transparent);
  filter: none;
  opacity: 0.42;
}

.driver-row-empty .bar-track {
  width: 100%;
  min-height: 12px;
  border: 1px solid var(--line);
  background: #ffffff;
  transition: background 140ms ease, border-color 140ms ease, box-shadow 140ms ease;
}

.driver-row-empty .bar-fill {
  background: transparent;
  opacity: 0;
  transition: background 140ms ease, opacity 140ms ease;
}

.driver-name-placeholder {
  display: none;
}

.driver-name {
  min-width: 0;
  font-weight: 400;
  overflow-x: auto;
  overflow-y: hidden;
  padding-bottom: 2px;
  scrollbar-width: thin;
  text-align: right;
  white-space: nowrap;
}

.driver-name::-webkit-scrollbar {
  height: 4px;
}

.driver-name::-webkit-scrollbar-track {
  background: transparent;
}

.driver-name::-webkit-scrollbar-thumb {
  border-radius: 999px;
  background: var(--line);
}

.bar-track {
  height: 10px;
  border-radius: 999px;
  background: var(--light-grey);
  overflow: hidden;
}

.bar-fill {
  height: 100%;
  border-radius: inherit;
  background: var(--driver-color, var(--primary));
}

.driver-impact-high {
  --driver-color: var(--accessible-ochre);
}

.driver-impact-intermediate {
  --driver-color: var(--heritage-rose);
}

.driver-impact-low {
  --driver-color: var(--jacaranda);
}

.metric-supporting {
  display: grid;
  gap: 10px;
  margin-top: 10px;
}

.metric-definitions {
  display: grid;
  gap: 6px;
  color: var(--charcoal);
  font-family: var(--font-sans);
  font-size: 0.84rem;
  line-height: 1.45;
}

.note-section-title {
  color: var(--ink);
  font-family: var(--font-sans);
  font-size: 0.98rem;
  font-style: normal;
  font-weight: 600;
  line-height: 1.25;
}

.metric-definitions p,
.metric-definitions ul {
  margin: 0;
}

.metric-definitions ul {
  display: grid;
  gap: 5px;
  padding-left: 18px;
}

.metric-definitions li {
  padding-left: 2px;
}

.metric-definitions strong {
  color: var(--ink);
  font-weight: 500;
}

.metric-legend {
  margin-top: 12px;
  padding-top: 10px;
  border-top: 1px solid var(--line);
}

.validation-panel .metric-legend {
  flex-direction: row;
  align-items: center;
  justify-content: flex-end;
  min-width: 0;
  justify-self: end;
  margin-top: 0;
  padding: 0;
  border-top: 0;
  border-left: 0;
  gap: 8px;
  line-height: 1.25;
}

.validation-panel table {
  min-width: 920px;
}

.validation-panel th:nth-child(n + 4),
.validation-panel td.metric-value {
  text-align: right;
}

.validation-panel td em {
  display: inline-flex;
  margin-left: 6px;
  padding: 2px 6px;
  border-radius: 999px;
  background: rgba(143, 158, 201, 0.2);
  color: var(--navy);
  font-size: 0.7rem;
  font-style: normal;
  font-weight: 600;
  vertical-align: middle;
}

.metric-value span {
  display: inline-flex;
  min-width: 4.2ch;
  justify-content: flex-end;
  padding: 0;
  border-radius: 0;
  background: transparent;
  font-weight: 600;
  line-height: 1.25;
}

.metric-value.metric-strong span {
  color: var(--metric-strong);
}

.metric-value.metric-adequate span {
  color: var(--metric-adequate);
}

.metric-value.metric-limited span {
  color: var(--metric-limited);
}

.metric-value.metric-unavailable {
  color: var(--muted);
}

.heatmap-legend {
  flex-direction: column;
  align-items: flex-end;
  justify-content: flex-end;
  min-width: 230px;
  margin-top: 0;
  padding-left: 16px;
  border-left: 1px solid var(--line);
  text-align: right;
  gap: 8px;
  line-height: 1.25;
}

.heatmap-legend > span {
  display: grid;
  grid-template-columns: minmax(102px, max-content) minmax(98px, 1fr);
  align-items: center;
  gap: 10px;
  width: 100%;
}

.heatmap-legend .legend-signal {
  display: inline-flex;
  align-items: center;
  justify-content: flex-start;
  gap: 7px;
  text-align: left;
}

.heatmap-legend .legend-range {
  color: var(--charcoal);
  text-align: right;
  white-space: nowrap;
}

.heatmap-footer {
  display: grid;
  grid-template-columns: minmax(0, 1fr) minmax(230px, max-content);
  align-items: end;
  gap: 16px;
  margin-top: 10px;
  margin-right: -28px;
}

.zscore-note {
  display: grid;
  gap: 4px;
  min-width: 0;
  padding: 0;
  background: transparent;
  color: var(--charcoal);
  font-size: 0.82rem;
  line-height: 1.35;
}

.zscore-note strong {
  display: inline-flex;
  align-items: baseline;
  gap: 6px;
  flex-wrap: wrap;
  color: var(--charcoal);
  font-size: 0.92rem;
  font-weight: 650;
}

.zscore-citation {
  color: var(--muted);
  font-size: 0.78rem;
}

.metric-legend .metric-strong {
  background: var(--metric-strong);
}

.metric-legend .metric-adequate {
  background: var(--metric-adequate);
}

.metric-legend .metric-limited {
  background: var(--metric-limited);
}

.whatif-grid {
  display: grid;
  gap: 10px;
}

.compact-field {
  min-height: 68px;
}

.whatif-result {
  display: grid;
  gap: 10px;
  margin-top: 14px;
}

.whatif-result div {
  display: flex;
  justify-content: space-between;
  gap: 10px;
  padding: 10px 0;
  border-top: 1px solid var(--line);
}

.whatif-result span {
  color: var(--muted);
  font-weight: 700;
}

.whatif-result strong {
  text-align: right;
}

.summary-note {
  display: grid;
  gap: 12px;
  margin-top: 16px;
}

.note-line {
  padding: 12px;
  border: 1px solid var(--primary);
  border-radius: 8px;
  background: var(--primary-soft);
  color: var(--charcoal);
  font-size: 0.88rem;
  line-height: 1.45;
}

.trajectory-chart {
  display: flex;
  align-items: end;
  gap: 10px;
  height: 260px;
  padding: 16px 8px 0;
  border-bottom: 1px solid var(--line);
}

.trajectory-bar {
  display: grid;
  align-items: end;
  width: 52px;
  min-height: 24px;
  border-radius: 8px 8px 0 0;
  background: var(--primary);
  color: #ffffff;
  text-align: center;
  font-weight: 800;
}

.table-wrap {
  overflow-x: auto;
}

table {
  width: 100%;
  min-width: 760px;
  border-collapse: collapse;
}

th,
td {
  padding: 12px;
  border-bottom: 1px solid var(--line);
  text-align: left;
}

th {
  color: var(--charcoal);
  font-size: 0.82rem;
  text-transform: uppercase;
}

.gene-list {
  flex: 1 1 auto;
  margin-top: 16px;
  min-height: 0;
  overflow-y: scroll;
  padding-right: 22px;
  scrollbar-color: var(--charcoal) transparent;
  scrollbar-gutter: stable both-edges;
  scrollbar-width: thin;
}

.gene-list::-webkit-scrollbar {
  width: 8px;
}

.gene-list::-webkit-scrollbar-track {
  background: transparent;
}

.gene-list::-webkit-scrollbar-thumb {
  border: 2px solid var(--surface);
  border-radius: 999px;
  background: var(--charcoal);
}

.gene-table {
  width: 100%;
  min-width: 0;
}

.gene-table-header,
.gene-item {
  display: grid;
  grid-template-columns: minmax(92px, 0.88fr) minmax(86px, 0.52fr) minmax(116px, 0.9fr) minmax(82px, 0.6fr);
  align-items: start;
  gap: 8px;
}

.gene-table-header {
  position: sticky;
  top: 0;
  z-index: 2;
  padding: 0 0 8px;
  border-bottom: 1px solid var(--line);
  background: var(--surface);
  color: var(--muted);
  font-size: 0.68rem;
  font-weight: 850;
  letter-spacing: 0;
  text-transform: uppercase;
}

.gene-item {
  padding: 10px 0;
  border-bottom: 1px solid var(--line);
  transition: background 160ms ease;
}

.gene-item.is-highlighted {
  margin: 0;
  border-radius: 0;
  background: rgba(252, 237, 226, 0.82);
  box-shadow: none;
  scroll-margin-block: 120px;
}

.gene-item span,
.gene-item a {
  color: var(--muted);
  line-height: 1.4;
}

.gene-item .gene-symbol-link {
  color: var(--charcoal);
  font-size: 0.94rem;
  font-weight: 400;
  overflow-wrap: anywhere;
  word-break: break-word;
  text-decoration: underline;
  text-decoration-thickness: 1px;
  text-underline-offset: 3px;
}

.gene-symbol-link:hover,
.gene-link-group a:hover {
  text-decoration-thickness: 2px;
}

.gene-metrics {
  display: grid;
  gap: 4px;
  color: var(--charcoal);
  font-size: 0.82rem;
  font-weight: 400;
  line-height: 1.35;
}

.gene-stage {
  display: flex;
  min-width: 0;
}

.gene-stage-badge {
  max-width: 100%;
  padding: 4px 7px;
  border: 1px solid var(--primary);
  border-radius: 7px;
  background: var(--primary-soft);
  color: var(--primary);
  font-size: 0.72rem;
  font-weight: 400;
  line-height: 1;
  overflow: hidden;
  text-overflow: ellipsis;
  white-space: nowrap;
}

.gene-stage-badge.stage-diagnosis {
  border-color: var(--primary);
  background: var(--primary-soft);
}

.gene-stage-badge.stage-progression {
  border-color: var(--primary);
  background: var(--primary-soft);
}

.gene-stage-badge.stage-response {
  border-color: var(--primary);
  background: var(--primary-soft);
}

.gene-link-group {
  display: grid;
  justify-content: flex-start;
  gap: 4px;
}

.gene-item .gene-link-group a {
  font-size: 0.72rem;
  font-weight: 400;
  text-decoration: underline;
  text-decoration-thickness: 1px;
  text-underline-offset: 3px;
}

.biomarker-grid > .panel {
  display: flex;
  flex-direction: column;
  height: 600px;
  min-height: 0;
  margin-top: 0;
}

.heatmap {
  display: grid;
  gap: 8px;
  margin-top: 0;
  min-width: 0;
  overflow: visible;
  padding: 0;
}

.heatmap .awaiting-run {
  margin: 0;
}

.zscore-chart-title {
  color: var(--charcoal);
  font-size: 0.92rem;
  font-weight: 650;
}

.zscore-frame {
  display: grid;
  grid-template-columns: 44px minmax(0, 1fr);
  gap: 8px;
  min-height: 342px;
  align-items: start;
}

.zscore-axis {
  position: relative;
  height: 270px;
  margin-top: 28px;
  color: var(--muted);
  font-size: 0.78rem;
  font-weight: 500;
}

.zscore-axis span {
  position: absolute;
  right: 0;
  top: var(--axis-y);
  transform: translateY(-50%);
  white-space: nowrap;
}

.zscore-scroll {
  overflow-x: scroll;
  overflow-y: visible;
  padding: 28px 10px 34px;
  scrollbar-color: var(--charcoal) transparent;
  scrollbar-gutter: stable;
  scrollbar-width: thin;
}

.zscore-scroll::-webkit-scrollbar {
  height: 8px;
}

.zscore-scroll::-webkit-scrollbar-track {
  background: transparent;
}

.zscore-scroll::-webkit-scrollbar-thumb {
  border: 2px solid #ffffff;
  border-radius: 999px;
  background: var(--charcoal);
}

.heatmap-strip {
  position: relative;
  height: 270px;
  min-width: max(100%, var(--heatmap-min-width, 0px));
  overflow: visible;
}

.zscore-gridline {
  position: absolute;
  right: 0;
  left: 0;
  top: var(--axis-y);
  border-top: 1px solid rgba(66, 66, 66, 0.16);
  pointer-events: none;
}

.zscore-gridline-zero {
  border-top-color: rgba(66, 66, 66, 0.28);
}

.zscore-bars {
  position: relative;
  z-index: 1;
  display: grid;
  grid-template-columns: repeat(var(--heatmap-count, 18), minmax(20px, 1fr));
  gap: 4px;
  height: 100%;
}

.zscore-frame-empty .zscore-scroll {
  pointer-events: none;
}

.zscore-plot-empty {
  opacity: 0.78;
}

.zscore-placeholder-bar {
  position: relative;
  display: block;
  height: 100%;
  min-width: 0;
}

.zscore-placeholder-bar::before {
  content: "";
  position: absolute;
  top: var(--placeholder-top);
  left: 50%;
  width: min(20px, 82%);
  height: max(7px, var(--placeholder-height));
  border: 1px dashed rgba(66, 66, 66, 0.22);
  border-radius: 5px;
  background: rgba(66, 66, 66, 0.05);
  transform: translateX(-50%);
}

.heatmap-item {
  --bar-color: var(--light-grey);
  --bar-tag-text: #000000;
  appearance: none;
  position: relative;
  display: block;
  height: 100%;
  width: 100%;
  padding: 0;
  border: 0;
  background: transparent;
  cursor: pointer;
  justify-items: center;
  min-width: 0;
}

.heatmap-item::before {
  content: "";
  position: absolute;
  left: 50%;
  z-index: 2;
  border-left: 1px dashed #8a8a8a;
  opacity: 0;
  pointer-events: none;
  transform: translateX(-50%);
  transition: opacity 140ms ease;
}

.heatmap-item.tag-positive::before {
  top: -22px;
  bottom: 50%;
}

.heatmap-item.tag-negative::before {
  top: 50%;
  bottom: -23px;
}

.heatmap-item:hover::before,
.heatmap-item:focus-visible::before {
  opacity: 1;
}

.heatmap-item.tag-positive .bar-hover-tag {
  top: -22px;
  bottom: auto;
}

.heatmap-item.tag-negative .bar-hover-tag {
  top: auto;
  bottom: -23px;
}

.heatmap-cell {
  position: absolute;
  top: var(--bar-top);
  left: 50%;
  z-index: 1;
  display: block;
  width: min(20px, 82%);
  height: max(4px, var(--bar-height));
  border-radius: 5px;
  background: var(--bar-color);
  transform: translateX(-50%);
  transition: box-shadow 140ms ease, transform 140ms ease;
}

.heatmap-item:hover .heatmap-cell,
.heatmap-item:focus-visible .heatmap-cell {
  box-shadow:
    0 0 0 4px color-mix(in srgb, var(--bar-color) 38%, transparent),
    0 12px 18px color-mix(in srgb, var(--bar-color) 26%, transparent);
  transform: translate(-50%, -3px);
}

.heatmap-item:focus-visible {
  outline: 0;
}

.toast {
  position: fixed;
  right: 20px;
  bottom: 20px;
  transform: translateY(18px);
  max-width: 320px;
  padding: 12px 14px;
  border-radius: 8px;
  background: var(--charcoal);
  color: #ffffff;
  opacity: 0;
  pointer-events: none;
  transition: opacity 160ms ease, transform 160ms ease;
}

.toast.visible {
  transform: translateY(0);
  opacity: 1;
}

@media (max-width: 1100px) {
  .app-shell,
  .app-shell.sidebar-collapsed {
    grid-template-columns: 1fr;
  }

  .sidebar {
    position: sticky;
    top: 0;
    z-index: 5;
    display: block;
    padding: 12px 14px;
    border-right: 0;
    border-bottom: 1px solid var(--sidebar-border);
    box-shadow: 0 4px 20px rgba(0, 0, 0, 0.1);
  }

  .brand-block,
  .sidebar-footer {
    display: none;
  }

  .sidebar-nav {
    padding: 0;
  }

  .nav-section-label {
    display: none;
  }

  .nav-list {
    display: flex;
    gap: 8px;
    overflow-x: auto;
    padding-bottom: 2px;
  }

  .nav-item,
  .sidebar-collapsed .nav-item {
    grid-template-columns: auto 1fr;
    justify-items: stretch;
    min-width: 190px;
    padding: 8px 10px;
  }

  .sidebar-collapsed .nav-label {
    display: inline;
  }

  .calculator-grid,
  .lower-grid,
  .lower-grid.lower-grid-two,
  .summary-grid,
  .pipeline-flow,
  .classification-grid,
  .credits-grid,
  .metric-supporting {
    grid-template-columns: 1fr;
  }

  .calculator-grid > .panel {
    height: auto;
    min-height: 0;
    overflow: visible;
  }

  .pipeline-step {
    grid-template-columns: 1fr;
    gap: 8px;
  }

  .validation-panel .metric-legend {
    flex-direction: row;
    align-items: center;
    justify-content: flex-end;
    justify-self: end;
    min-width: 0;
    padding: 10px 0 0;
    border-top: 1px solid var(--line);
    border-left: 0;
  }

  .biomarker-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
    overflow-x: visible;
  }

  .csv-panel,
  .result-panel {
    height: auto;
  }

  .fingerprint-drivers {
    flex: 0 1 auto;
    min-height: 220px;
  }

  .driver-list {
    min-height: 180px;
    max-height: 260px;
  }
}

@media (max-width: 720px) {
  .workspace {
    padding: 16px;
  }

  .topbar,
  .panel-heading,
  .upload-strip,
  .risk-visual,
  .action-row {
    align-items: stretch;
    flex-direction: column;
    grid-template-columns: 1fr;
  }

  .field-grid,
  .model-output-grid {
    grid-template-columns: 1fr;
  }

  .biomarker-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
    overflow-x: visible;
  }

  .member-row {
    grid-template-columns: 1fr;
  }

  .risk-ring {
    width: 160px;
    height: 160px;
    margin: 0 auto;
  }

  .driver-row {
    grid-template-columns: 1fr;
  }

  .fingerprint {
    grid-template-columns: repeat(9, 1fr);
  }

  .csv-model-results {
    grid-template-columns: 1fr;
  }

  .csv-dropzone {
    padding: 22px 16px;
  }
}